Endocrine Abstracts

There are considerable variations in diagnosis and therapeutical practices in hyperthyroidism (HT) between countries. Few of these differences rely on a scientific basis. we present the results of a study conducted among a representative sample of 263 French endocrinologists. All consecutive patients seen for HT during the study period were included. Symptoms, biological data and treatment were recorded. 1214 patients with hyperthyroidism were included, 1144 had an identified ...

SH is defined by a decrease of TSH with normal thyroid hormone (TH) concentrations. The clinical picture is not clear, whether these patients may have symptoms or alterations of QoL. It is well known that in overt hyperthyroidism, symptoms may be absent in old patients. In SH, one study in young patients has reported an increased symptom score and a slight decrease of QoL but these results have not been confirmed in middle-aged subjects. We report the initial data of the Pirat...

Premature ovarian failure (POF) is a common cause of female infertility affecting about 1–2% of women under the age of 40. This heterogeneous disorder is characterized by primary or secondary amenorrhea and elevated gonadotropin values. Several defects can cause POF, including autoimmunity, X chromosome abnormalities and gene mutations, but its pathogenesis is still unknown in the vast majority of women with normal karyotype. We recently described two sisters affected wit...